What's the Problem?

Osteoporosis affects 200 million people worldwide and occurs when the body removes more bone than it regenerates, weakening the bone structure and increasing the risk of fractures. Patients are typically treated with bisphosphonates, which inhibit the action of osteoclasts responsible for bone resorption. However, the low blood supply to bone tissue makes it difficult for the medication to reach its target effectively, requiring higher doses and increasing the risk of serious side effects in other areas of the body.

How are they Solving it?

At APASOMICs, we have developed Apasomas, an innovative drug delivery system inspired by the natural process of bone remineralization. These hydroxyapatite nanospheres are designed to transport drugs like bisphosphonates directly to the bone in a more efficient and targeted manner. Apasomas offer unique advantages: they are non-immunogenic due to their inorganic composition, highly stable, and capable of effectively penetrating bone tissue. Additionally, their dual capability allows them to remineralize bone while delivering the drug, opening the possibility of not only halting the progression of diseases like osteoporosis but also reversing the damage caused.

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